A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells

Scalable methods of recombinant adeno-associated virus (rAAV) production have gained much recent interest as the field of rAAV-mediated gene therapy approaches the clinic. In particular, the production of rAAV vectors in insect cells via the use of recombinant baculovirus technology has proven to be...

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Bibliografiske detaljer
Main Authors: Smith, Richard H, Levy, Justin R, Kotin, Robert M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835045/
https://ncbi.nlm.nih.gov/pubmed/19532142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.128
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