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A New Potent Secondary Amphipathic Cell–penetrating Peptide for siRNA Delivery Into Mammalian Cells

RNA interference constitutes a powerful tool for biological studies, but has also become one of the most challenging therapeutic strategies. However, small interfering RNA (siRNA)-based strategies suffer from their poor delivery and biodistribution. Cell-penetrating peptides (CPPs) have been shown t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Crombez, Laurence, Aldrian-Herrada, Gudrun, Konate, Karidia, Nguyen, Quan N, McMaster, Gary K, Brasseur, Robert, Heitz, Frederic, Divita, Gilles
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834975/
https://ncbi.nlm.nih.gov/pubmed/18957965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.215
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