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The dysregulation of intracellular calcium in Alzheimer disease

Alzheimer disease (AD) is the most common neurodegenerative disorder worldwide and is at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD brain are thought to trigger the extensive synaptic loss and neurodegeneration linked to cognitive decline, an idea that u...

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Autores principales: Supnet, Charlene, Bezprozvanny, Ilya
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834825/
https://ncbi.nlm.nih.gov/pubmed/20080301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.12.014
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