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The dysregulation of intracellular calcium in Alzheimer disease
Alzheimer disease (AD) is the most common neurodegenerative disorder worldwide and is at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD brain are thought to trigger the extensive synaptic loss and neurodegeneration linked to cognitive decline, an idea that u...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834825/ https://ncbi.nlm.nih.gov/pubmed/20080301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.12.014 |
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