Mosaic Vaccines Elicit CD8+ T lymphocyte Responses in Monkeys that Confer Enhanced Immune Coverage of Diverse HIV Strains

An effective HIV vaccine must elicit immune responses that recognize genetically diverse viruses1, 2. It must generate CD8+ T lymphocytes that control HIV replication and CD4+ T lymphocytes that provide help for the generation and maintenance of both cellular and humoral immune responses against the...

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Hlavní autoři: Santra, Sampa, Liao, Hua-Xin, Zhang, Ruijin, Muldoon, Mark, Watson, Sydeaka, Fischer, Will, Theiler, James, Szinger, James, Balachandran, Harikrishnan, Buzby, Adam, Quinn, David, Parks, Robert J., Tsao, Chun-Yen, Carville, Angela, Mansfield, Keith G., Pavlakis, George N., Felber, Barbara K., Haynes, Barton F., Korber, Bette T., Letvin, Norman L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834806/
https://ncbi.nlm.nih.gov/pubmed/20173754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2108
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