Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost

An effective human immunodeficiency virus type 1 (HIV-1) vaccine must induce protective antibody responses, as well as CD4(+) and CD8(+) T cell responses, that can be effective despite extraordinary diversity of HIV-1. The consensus and mosaic immunogens are complete but artificial proteins, computa...

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Vydáno v:J Virol
Hlavní autoři: Hulot, Sandrine L., Korber, Bette, Giorgi, Elena E., Vandergrift, Nathan, Saunders, Kevin O., Balachandran, Harikrishnan, Mach, Linh V., Lifton, Michelle A., Pantaleo, Giuseppe, Tartaglia, Jim, Phogat, Sanjay, Jacobs, Bertram, Kibler, Karen, Perdiguero, Beatriz, Gomez, Carmen E., Esteban, Mariano, Rosati, Margherita, Felber, Barbara K., Pavlakis, George N., Parks, Robert, Lloyd, Krissey, Sutherland, Laura, Scearce, Richard, Letvin, Norman L., Seaman, Michael S., Alam, S. Munir, Montefiori, David, Liao, Hua-Xin, Haynes, Barton F., Santra, Sampa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474309/
https://ncbi.nlm.nih.gov/pubmed/25855741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00383-15
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