Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost

An effective human immunodeficiency virus type 1 (HIV-1) vaccine must induce protective antibody responses, as well as CD4(+) and CD8(+) T cell responses, that can be effective despite extraordinary diversity of HIV-1. The consensus and mosaic immunogens are complete but artificial proteins, computa...

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Опубликовано в: :J Virol
Главные авторы: Hulot, Sandrine L., Korber, Bette, Giorgi, Elena E., Vandergrift, Nathan, Saunders, Kevin O., Balachandran, Harikrishnan, Mach, Linh V., Lifton, Michelle A., Pantaleo, Giuseppe, Tartaglia, Jim, Phogat, Sanjay, Jacobs, Bertram, Kibler, Karen, Perdiguero, Beatriz, Gomez, Carmen E., Esteban, Mariano, Rosati, Margherita, Felber, Barbara K., Pavlakis, George N., Parks, Robert, Lloyd, Krissey, Sutherland, Laura, Scearce, Richard, Letvin, Norman L., Seaman, Michael S., Alam, S. Munir, Montefiori, David, Liao, Hua-Xin, Haynes, Barton F., Santra, Sampa
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474309/
https://ncbi.nlm.nih.gov/pubmed/25855741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00383-15
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