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Mechanism of Folding Chamber Closure in a Group II Chaperonin

Group II chaperonins are essential mediators of cellular protein folding in eukaryotes and archaea. These oligomeric protein machines, ~1MDa, consist of two back-to-back rings encompassing a central cavity that accommodates polypeptide substrates1,2,3. Chaperonin-mediated protein folding is critical...

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Библиографические подробности
Главные авторы: Zhang, Junjie, Baker, Matthew L., Schröder, Gunnar F., Douglas, Nicholai R., Reissmann, Stefanie, Jakana, Joanita, Dougherty, Matthew, Fu, Caroline J., Levitt, Michael, Ludtke, Steven J., Frydman, Judith, Chiu, Wah
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834796/
https://ncbi.nlm.nih.gov/pubmed/20090755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08701
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