Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours

BACKGROUND: The expression of Keratin 19 (K19) was reported in a subset of hepatocellular carcinomas (HCCs). K19 positive HCCs are associated with an increased malignancy compared to K19 negative HCCs. No suitable mouse models exist for this subtype of HCC, nor is the incidence of K19 expression in...

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Autors principals: van Sprundel, Renee GHM, van den Ingh, Ted SGAM, Desmet, Valeer J, Katoonizadeh, Azeam, Penning, Louis C, Rothuizen, Jan, Roskams, Tania, Spee, Bart
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834617/
https://ncbi.nlm.nih.gov/pubmed/20167095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-9-4
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