Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours

BACKGROUND: The expression of Keratin 19 (K19) was reported in a subset of hepatocellular carcinomas (HCCs). K19 positive HCCs are associated with an increased malignancy compared to K19 negative HCCs. No suitable mouse models exist for this subtype of HCC, nor is the incidence of K19 expression in...

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Détails bibliographiques
Auteurs principaux: van Sprundel, Renee GHM, van den Ingh, Ted SGAM, Desmet, Valeer J, Katoonizadeh, Azeam, Penning, Louis C, Rothuizen, Jan, Roskams, Tania, Spee, Bart
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834617/
https://ncbi.nlm.nih.gov/pubmed/20167095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-9-4
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