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The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most worldwide frequent primary carcinomas resulting in the death of many cirrhotic patients. Unfortunately, the molecular mechanisms of this cancer are not well understood; therefore, we need a good model system to study HCC. The dog is recog...

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Autores principales: Boomkens, Sacha Y, Spee, Bart, IJzer, Jooske, Kisjes, Ronald, Egberink, Herman F, van den Ingh, Ted SGAM, Rothuizen, Jan, Penning, Louis C
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC535891/
https://ncbi.nlm.nih.gov/pubmed/15566568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-3-9
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