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A Spleen Tyrosine Kinase Inhibitor Reduces the Severity of Established Glomerulonephritis

Antibody-mediated glomerulonephritis, including that resulting from immune complexes, is an important cause of renal failure and is in need of more specific and effective treatment. Binding of antibody or immune complexes to Fc receptors activates intracellular signal transduction pathways, includin...

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Autors principals: Smith, Jennifer, McDaid, John P., Bhangal, Gurjeet, Chawanasuntorapoj, Ratana, Masuda, Esteban S., Cook, H. Terence, Pusey, Charles D., Tam, Frederick W.K.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834545/
https://ncbi.nlm.nih.gov/pubmed/19959716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009030263
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