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A Spleen Tyrosine Kinase Inhibitor Reduces the Severity of Established Glomerulonephritis

Antibody-mediated glomerulonephritis, including that resulting from immune complexes, is an important cause of renal failure and is in need of more specific and effective treatment. Binding of antibody or immune complexes to Fc receptors activates intracellular signal transduction pathways, includin...

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Bibliografiske detaljer
Main Authors: Smith, Jennifer, McDaid, John P., Bhangal, Gurjeet, Chawanasuntorapoj, Ratana, Masuda, Esteban S., Cook, H. Terence, Pusey, Charles D., Tam, Frederick W.K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834545/
https://ncbi.nlm.nih.gov/pubmed/19959716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009030263
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