Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD

Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR (eGFR). Whether uromodulin levels associate with UMOD variants or with the risk for developing CKD is unknown. We conducted an age- and gend...

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Autores principales: Köttgen, Anna, Hwang, Shih-Jen, Larson, Martin G., Van Eyk, Jennifer E., Fu, Qin, Benjamin, Emelia J., Dehghan, Abbas, Glazer, Nicole L., Kao, W.H. Linda, Harris, Tamara B., Gudnason, Vilmundur, Shlipak, Michael G., Yang, Qiong, Coresh, Josef, Levy, Daniel, Fox, Caroline S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2010
Materias:
Clinical Epidemiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834540/
https://ncbi.nlm.nih.gov/pubmed/19959715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070725
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