Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD

Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR (eGFR). Whether uromodulin levels associate with UMOD variants or with the risk for developing CKD is unknown. We conducted an age- and gend...

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Autori principali: Köttgen, Anna, Hwang, Shih-Jen, Larson, Martin G., Van Eyk, Jennifer E., Fu, Qin, Benjamin, Emelia J., Dehghan, Abbas, Glazer, Nicole L., Kao, W.H. Linda, Harris, Tamara B., Gudnason, Vilmundur, Shlipak, Michael G., Yang, Qiong, Coresh, Josef, Levy, Daniel, Fox, Caroline S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
Soggetti:
Clinical Epidemiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834540/
https://ncbi.nlm.nih.gov/pubmed/19959715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070725
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