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Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD

Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR (eGFR). Whether uromodulin levels associate with UMOD variants or with the risk for developing CKD is unknown. We conducted an age- and gend...

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Detalhes bibliográficos
Main Authors: Köttgen, Anna, Hwang, Shih-Jen, Larson, Martin G., Van Eyk, Jennifer E., Fu, Qin, Benjamin, Emelia J., Dehghan, Abbas, Glazer, Nicole L., Kao, W.H. Linda, Harris, Tamara B., Gudnason, Vilmundur, Shlipak, Michael G., Yang, Qiong, Coresh, Josef, Levy, Daniel, Fox, Caroline S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834540/
https://ncbi.nlm.nih.gov/pubmed/19959715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070725
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