Abnormal DNA Patterns in Animal Mitochondria: Ethidium Bromide-Induced Breakdown of Closed Circular DNA and Conditions Leading to Oligomer Accumulation
Treatment of cultured mouse fibroblasts (L-cells) and hamster kidney cells with ethidium bromide was found to inhibit the incorporation of [(3)H]thymidine into mitochondrial closed-circular DNA, but not into nuclear DNA. The specific activity of nuclear DNA in treated cells was higher than in contro...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1970
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283449/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4321352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.4.1926 |
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