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Abnormal DNA Patterns in Animal Mitochondria: Ethidium Bromide-Induced Breakdown of Closed Circular DNA and Conditions Leading to Oligomer Accumulation

Treatment of cultured mouse fibroblasts (L-cells) and hamster kidney cells with ethidium bromide was found to inhibit the incorporation of [(3)H]thymidine into mitochondrial closed-circular DNA, but not into nuclear DNA. The specific activity of nuclear DNA in treated cells was higher than in contro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Nass, Margit M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4321352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.4.1926
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