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Abnormal DNA Patterns in Animal Mitochondria: Ethidium Bromide-Induced Breakdown of Closed Circular DNA and Conditions Leading to Oligomer Accumulation
Treatment of cultured mouse fibroblasts (L-cells) and hamster kidney cells with ethidium bromide was found to inhibit the incorporation of [(3)H]thymidine into mitochondrial closed-circular DNA, but not into nuclear DNA. The specific activity of nuclear DNA in treated cells was higher than in contro...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1970
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283449/ https://ncbi.nlm.nih.gov/pubmed/4321352 |
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