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The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells
Affinity maturation of the immune response and the generation of long-lived bone marrow (BM) plasma cells are hallmarks of CD40-dependent, thymus-dependent (TD) humoral immunity. Through disruption of the tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6)-binding site within the CD40...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834483/ https://ncbi.nlm.nih.gov/pubmed/11967542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni792 |
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