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Short-circuiting long-lived humoral immunity by the heightened engagement of CD40
Agonistic αCD40 Ab’s have been shown to be potent immune adjuvants for both cell- and humoral-mediated immunity. While enhancing short-lived humoral immunity, the administration of a CD40 agonist during thymus-dependent immune responses ablates germinal center formation, prematurely terminates the h...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150892/ https://ncbi.nlm.nih.gov/pubmed/11877469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14110 |
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