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The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation

Mammals compensate X chromosome gene dosage between the sexes by silencing of one of the two female X chromosomes. X inactivation is initiated in the early embryo and requires the non-coding Xist RNA, which encompasses the inactive X chromosome (Xi) and triggers its silencing. In differentiated cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pullirsch, Dieter, Härtel, Renate, Kishimoto, Hiroyuki, Leeb, Martin, Steiner, Günter, Wutz, Anton
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834461/
https://ncbi.nlm.nih.gov/pubmed/20150277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.035956
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