Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice

To determine whether the calcium-sensing receptor (CaR) participates in tooth formation and dental alveolar bone development in mandibles in vivo, we examined these processes, as well as mineralization, in 2-week-old CaR-knockout (CaR(−/−)) mice. We also attempted to rescue the phenotype of CaR(−/−)...

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Main Authors: Sun, Wen, Sun, Weiwei, Liu, Jingning, Zhou, Xichao, Xiao, Yongjun, Karaplis, Andrew, Pollak, Martin R., Brown, Edward, Goltzman, David, Miao, Dengshun
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2010
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834458/
https://ncbi.nlm.nih.gov/pubmed/20150282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.045898
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