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Absence of PTHrP Nuclear Localization and Carboxyl Terminus Sequences Leads to Abnormal Brain Development and Function

We assessed whether the nuclear localization sequences (NLS) and C terminus of parathyroid hormone-related protein (PTHrP) play critical roles in brain development and function. We used histology, immunohistochemistry, histomorphometry, Western blots and electrophysiological recordings to compare th...

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Detalhes bibliográficos
Main Authors: Gu, Zhen, Liu, Yahong, Zhang, Yongjie, Jin, Shulei, Chen, Qi, Goltzman, David, Karaplis, Andrew, Miao, Dengshun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402381/
https://ncbi.nlm.nih.gov/pubmed/22844494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041542
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