An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

Human plasma cells (PCs) and their precursors play an essential role in humoral immune response, but are rare and difficult to harvest. We report here i) the generation of human syndecan-1(+) and immunoglobulin secreting PCs starting from memory B cells (MBCs) in a 3-step- and 10-day (D) culture, in...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Jourdan, Michel, Caraux, Anouk, De Vos, John, Fiol, Geneviève, Larroque, Marion, Cognot, Chantal, Bret, Caroline, Duperray, Christophe, Hose, Dirk, Klein, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834398/
https://ncbi.nlm.nih.gov/pubmed/19846886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235960
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky