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Insight into intra- and inter-molecular interactions of PKC: design of specific modulators of kinase function

Protein kinase C (PKC) is a family of kinases that are critical in many cellular events. These enzymes are activated by lipid-derived second messengers, are dependent on binding to negatively charged phospholipids and some members also require calcium to attain full activation. The interaction with...

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Bibliografiske detaljer
Main Authors: Kheifets, Viktoria, Mochly-Rosen, Daria
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834269/
https://ncbi.nlm.nih.gov/pubmed/17580120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2007.04.014
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