Neutralizing IL-17 during re-activation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and IL-1

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• IL-1-dependent cartilage damage in a macrophage-driven arthritis model can be circumvented by T cell IL-17
  gan: Koenders, MI, et al.
  Cyhoeddwyd: (2004)
• Neutralizing synovial RANKL by local OPG gene therapy in collagen-induced arthritis prevents cartilage erosion through induction of a non-destructive type 2 synovitis
  gan: Lubberts, E, et al.
  Cyhoeddwyd: (2004)
• Blocking of Interleukin-17 during Reactivation of Experimental Arthritis Prevents Joint Inflammation and Bone Erosion by Decreasing RANKL and Interleukin-1
  gan: Koenders, Marije I., et al.
  Cyhoeddwyd: (2005)
• Local IL-17 gene therapy accelerates collagen arthritis with severe bone erosion and rank ligand and rank expression in synovial infiltrate and at bone erosion sites
  gan: Lubberts, E, et al.
  Cyhoeddwyd: (2001)
• TNF-α dependency of IL-17-induced joint pathology differs under naive and arthritis conditions in vivo
  gan: Koenders, M, et al.
  Cyhoeddwyd: (2003)