Neutralizing IL-17 during re-activation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and IL-1

Por Koenders, MI, Lubberts, E, Joosten, LAB, van den Berg, WB
Publicado em 2005

Reporter cell lines for real-time imaging of NF-κB activation in the arthritic joint

Por Smeets, RL, Joosten, LAB, van den Berg, WB, van de Loo, FAJ
Publicado em 2004

Suppressor of cytokine signaling (SOCS)-3 gene transfer protects against collagen-induced arthritis

Por van de Loo, FAJ, Smeets, RL, Joosten, LAB, van den Berg, WB
Publicado em 2004

IL-1-dependent cartilage damage in a macrophage-driven arthritis model can be circumvented by T cell IL-17

Por Koenders, MI, Lubberts, E, Joosten, LAB, Kolls, JK, van den Berg, WB
Publicado em 2004

Endogenous IL-12p40 is crucial for antigen-induced arthritis and is partly involved in chronic relapsing streptococcal-cell-wall arthritis

Por Jacobs, M, Joosten, L, Helsen, MMA, Lubberts, E, van den Berg, WB
Publicado em 2003

IL-13 overexpression during immune complex arthritis diminishes MMP-mediated VDIPEN expression

Por Nabbe, KC, van Lent, PL, Holthuysen, AE, Koch, AE, van den Berg, WB
Publicado em 2004

Identification of a natural soluble form of the IL-18 receptor accessory protein as an immunomodulator in experimental arthritis

Por Smeets, RL, Arntz, OJ, Bennink, MB, van den Berg, WB, van de Loo, FAJ
Publicado em 2005

The inhibitory receptor FcγRII reduces joint inflammation in immune complex arthritis not only by inhibition of activatory FcγR but also by efficient clearance of immune complexes...

Por van Lent, PL, Nabbe, K, Blom, AB, Holthuysen, AE, Verbeek, S, van den Berg, WB
Publicado em 2003

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity

Por Blaney Davidson, EN, Scharstuhl, A, Vitters, EL, van der Kraan, PM, van den Berg, WB
Publicado em 2005

Expression of Toll-like receptor (TLR) 2, TLR3, TLR4 and TLR7 is increased in rheumatoid arthritis synovium and regulates cytokine production by dendritic cells upon stimulation of...

Por Roelofs, MF, Joosten, LAB, Abdollahi-Roodsaz, S, van Lieshout, AWT, Radstake, TRDJ, van den Berg, WB
Publicado em 2005

Oxygen radical production determines chondrocyte death and regulates matrix metalloproteinase-mediated matrix degradation during interferon gamma-accelerated immune complex arthrit...

Por van Lent, PLEM, Nabbe, KCAM, Holthuysen, AEM, Kolls, JK, Holland, SM, van den Berg, WB
Publicado em 2005

Activating FcγRIII determines cartilage destruction during immune complex arthritis but not in the presence of T-cell immunity

Por van Lent, PLEM, Nabbe, K, Blom, AB, Holthuysen, AEM, Verbeek, JS, van den Berg, WB
Publicado em 2002

Interleukin-1 receptor antagonist lentiviral gene transfer to the murine knee joint ameliorates collagen-induced arthritis

Por van de Loo, FAJ, Delavallee, LM, Arntz, OJ, Bennink, MB, Joosten, LAB, van den Berg, WB
Publicado em 2005

Requirement of local synovial IL-17 receptor signaling in the progression of chronic synovitis and bone erosion in arthritis

Por Lubberts, E, Huang, W, Schwarzenberger, P, Schurr, J, Peschon, J, van den Berg, WB, Kolls, JK
Publicado em 2004

Requirement of IL-17 receptor signaling in resident synoviocytes for development of full blown destructive arthritis

Por Lubberts, E, Schwarzenberger, P, Huang, W, Schurr, JR, Peschon, JJ, van den Berg, WB, Kolls, JK
Publicado em 2005

IL-18 directly promotes joint inflammation and induces cartilage destruction through IL-1

Por Joosten, L, Lubberts, E, Wagenmans, MJM, Helsen, MMA, van de Loo, FAJ, van den Berg, WB
Publicado em 2003

Local inhibition of endogenous IL-18 through adenoviral overexpression of IL-18BPc results in reduced incidence and severity of collagen induced arthritis in mice

Por Smeets, RL, van de Loo, AAJ, Joosten, LAB, Arntz, AJ, Bennink, MB, van den Berg, WB
Publicado em 2002

FcγRI up-regulation induced by local adenoviral-mediated IFN-γ production aggravates chondrocyte death during immune-complex-mediated arthritis

Por Nabbe, K, van Lent, PL, Holthuysen, AE, Sloetjes, AW, Kolls, J, Verbeek, JS, van den Berg, WB
Publicado em 2003

Local interleukin-12 gene transfer promotes conversion of an acute to a chronic destructive murine streptococcal cell wall arthritis

Por Joosten, LAB, Heuvelmans-Jacobs, M, Lubberts, E, van de Loo, FAJ, Helsen, MMA, van den Berg, WB
Publicado em 2001

Adenoviral transfer of murine OncostatinM induces inflammation and bone apposition in joints of IL-1, IL-6 and TNF-α deficient mice

Por de Hooge, ASK, van de Loo, FAJ, Bennink, M, Richards, CD, Arntz, OJ, van den Berg, WB
Publicado em 2002