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DNA Ligase Mutants of Escherichia coli

A procedure is described for the isolation of Escherichia coli mutants with either excess or deficient DNA ligase activity. A mutant that overproduces DNA ligase supports the growth of ligase-defective (gene 30 mutant) T4 phages. Even T4 rII-gene 30 double mutants, which are able to grow in normal E...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gellert, Martin, Bullock, Minnie L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1970
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283393/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4922293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1580
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