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A Conditional Lethal Mutant of Escherichia coli K12 Defective in the 5′ → 3′ Exonuclease Associated with DNA Polymerase I

A mutant strain of E. coli, initially identified by an abnormally high frequency of recombination, has been found to be defective in the 5′ → 3′ exonuclease associated with DNA polymerase I, but not in the polymerase activity. This defect is tolerated at 30°, but is lethal at 43°. Like other polymer...

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Detalhes bibliográficos
Main Authors: Konrad, E. Bruce, Lehman, I. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388383/
https://ncbi.nlm.nih.gov/pubmed/4600786
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