Heme Biosynthesis in Intermittent Acute Porphyria: Decreased Hepatic Conversion of Porphobilinogen to Porphyrins and Increased Delta Aminolevulinic Acid Synthetase Activity

Hepatic conversion of porphobilinogen to porphyrins was less than 50% of control levels in human subjects with the genetic disease, intermittent acute porphyria. This relative block in heme biosynthesis may be relevant to a concomitant 6- to 10-fold elevation in δ-aminolevulinic acid synthetase acti...

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Bibliografiske detaljer
Main Authors: Strand, L. James, Felsher, Bertram F., Redeker, Allan G., Marver, Harvey S.
Format: Artigo
Sprog:Inglês
Udgivet: 1970
Fag:
Biological Sciences: Medical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC283354/
https://ncbi.nlm.nih.gov/pubmed/5274461
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