Ethanol Exposure Depletes Hepatic Pigment Epithelium-Derived Factor, a Novel Lipid Regulator

BACKGROUND & AIMS: Ethanol abuse can lead to hepatic steatosis and evolve into cirrhosis and hepatocellular carcinoma. Pigment epithelium-derived factor (PEDF) is a multifunctional secreted glycoprotein that is expressed by hepatocytes. Proteomic, experimental, and clinical studies implicate PED...

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Main Authors: Chung, Chuhan, Shugrue, Christine, Nagar, Anil, Doll, Jennifer A., Cornwell, Mona, Gattu, Arijeet, Kolodecik, Tom, Pandol, Stephen J., Gorelick, Fred
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833423/
https://ncbi.nlm.nih.gov/pubmed/18996124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.09.065
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