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Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II

Recent work has shown that the RNA polymerase II enzyme pauses at a promoter-proximal site of many genes in Drosophila and mammals. This rate-limiting step occurs after recruitment and initiation of RNA polymerase II at a gene promoter. This stage in early elongation appears to be an important and b...

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Main Authors: Core, Leighton J., Lis, John T.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833332/
https://ncbi.nlm.nih.gov/pubmed/18369138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1150843
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