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Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II
Recent work has shown that the RNA polymerase II enzyme pauses at a promoter-proximal site of many genes in Drosophila and mammals. This rate-limiting step occurs after recruitment and initiation of RNA polymerase II at a gene promoter. This stage in early elongation appears to be an important and b...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833332/ https://ncbi.nlm.nih.gov/pubmed/18369138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1150843 |
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