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Amyloid Precursor Protein Regulates Ca(v)1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-Term Plasticity
Amyloid precursor protein (APP) has been strongly implicated in the pathogenesis of Alzheimer's disease (AD). Although impaired synaptic function is believed to be an early and causative event in AD, how APP physiologically regulates synaptic properties remains poorly understood. Here, we repor...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833283/ https://ncbi.nlm.nih.gov/pubmed/20016080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4104-09.2009 |
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