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Activation of JAK-STAT and Nitric Oxide Signaling as a Mechanism for Donor Heart Dysfunction
BACKGROUND: Donor heart dysfunction (DHD) precluding procurement for transplantation occurs in up to 25% of brain dead (BD) donors. The molecular mechanisms of DHD remain unclear. We investigated the potential role of myocardial interleukin (IL)-6 signaling through the JAK2-STAT3 pathway which can l...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833227/ https://ncbi.nlm.nih.gov/pubmed/20022263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2009.09.007 |
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