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Reversal of Impaired Myocardial β-Adrenergic Receptor Signaling By Continuous-Flow Left Ventricular Assist Device Support

BACKGROUND: Myocardial β-adrenergic receptor (β-AR) signaling is severely impaired in chronic heart failure (HF). The objective of this study is to determine if LV β-AR signaling can be restored following continuous-flow LVAD support. METHODS: Paired LV biopsies were obtained at the time of HeartMat...

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Detalhes bibliográficos
Main Authors: Akhter, Shahab A., D’Souza, Karen M., Malhotra, Ricky, Staron, Michelle L., Valeroso, Tracy B., Fedson, Savitri E., Anderson, Allen S., Raman, Jai, Jeevanandam, Valluvan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876229/
https://ncbi.nlm.nih.gov/pubmed/20202864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2010.01.010
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