G Protein-coupled Receptor Kinase-2 Is a Novel Regulator of Collagen Synthesis in Adult Human Cardiac Fibroblasts

Cardiac fibroblasts (CF) make up 60–70% of the total cell number in the heart and play a critical role in regulating normal myocardial function and in adverse remodeling following myocardial infarction and the transition to heart failure. Recent studies have shown that increased intracellular cAMP c...

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Detalhes bibliográficos
Main Authors: D'Souza, Karen M., Malhotra, Ricky, Philip, Jennifer L., Staron, Michelle L., Theccanat, Tiju, Jeevanandam, Valluvan, Akhter, Shahab A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083230/
https://ncbi.nlm.nih.gov/pubmed/21357420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.218263
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