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Conformational Significance of the Intrachain Disulfide Linkages in Immunoglobulins

Biophysical studies of intact immunoglobulins, enzymatically derived immunoglobulin subunits, and chemically derived immunoglobulin chains are reported. All the forms studied lacked optical activity associated with the α-helix conformation. A dichroism band centered near 217 nm, which has been assig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Litman, G. W., Good, R. A., Frommel, D., Rosenberg, A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1970
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC283320/
https://ncbi.nlm.nih.gov/pubmed/4098723
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