Conformational Significance of the Intrachain Disulfide Linkages in Immunoglobulins

Biophysical studies of intact immunoglobulins, enzymatically derived immunoglobulin subunits, and chemically derived immunoglobulin chains are reported. All the forms studied lacked optical activity associated with the α-helix conformation. A dichroism band centered near 217 nm, which has been assig...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Litman, G. W., Good, R. A., Frommel, D., Rosenberg, A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1970
Assuntos:	Biological Sciences: Biochemistry
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4098723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1085
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