Conformational Significance of the Intrachain Disulfide Linkages in Immunoglobulins
Biophysical studies of intact immunoglobulins, enzymatically derived immunoglobulin subunits, and chemically derived immunoglobulin chains are reported. All the forms studied lacked optical activity associated with the α-helix conformation. A dichroism band centered near 217 nm, which has been assig...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1970
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4098723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1085 |
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