A Stimulatory Thyrotropin Receptor Antibody (M22) and Thyrotropin Increase Interleukin-6 Expression and Secretion in Graves' Orbital Preadipocyte Fibroblasts

BACKGROUND: Patients with Graves' ophthalmopathy (GO) have circulating autoantibodies directed against the thyrotropin receptor (TSHR) and elevated levels of the proinflammatory cytokine interleukin-6 (IL-6) in both serum and orbital tissues. We hypothesized that these autoantibodies might incr...

Full description

Saved in:
Bibliographic Details
Main Authors: Kumar, Seema, Schiefer, Reagan, Coenen, Michael J., Bahn, Rebecca S.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
Subjects:
Original Studies, Reviews, and Scholarly Dialog
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833174/
https://ncbi.nlm.nih.gov/pubmed/20017620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2009.0278
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items