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Sensorimotor Gating of Schizophrenia Patients Depends on Catechol O-Methyltransferase Val(158)Met Polymorphism

It has been recently shown that Catechol O-methyltransferase (COMT) Val(158)Met polymorphism strongly influences prepulse inhibition (PPI) of the acoustic startle response (ASR) in healthy human volunteers. Given that schizophrenia patients exhibit impairment in PPI and that COMT is a putative susce...

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Autores principales: Quednow, Boris B., Wagner, Michael, Mössner, Rainald, Maier, Wolfgang, Kühn, Kai-Uwe
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833112/
https://ncbi.nlm.nih.gov/pubmed/18635674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbn088
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