Sensorimotor Gating of Schizophrenia Patients Depends on Catechol O-Methyltransferase Val(158)Met Polymorphism

It has been recently shown that Catechol O-methyltransferase (COMT) Val(158)Met polymorphism strongly influences prepulse inhibition (PPI) of the acoustic startle response (ASR) in healthy human volunteers. Given that schizophrenia patients exhibit impairment in PPI and that COMT is a putative susce...

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Bibliographic Details
Main Authors: Quednow, Boris B., Wagner, Michael, Mössner, Rainald, Maier, Wolfgang, Kühn, Kai-Uwe
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833112/
https://ncbi.nlm.nih.gov/pubmed/18635674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbn088
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