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Sensorimotor Gating of Schizophrenia Patients Depends on Catechol O-Methyltransferase Val(158)Met Polymorphism

It has been recently shown that Catechol O-methyltransferase (COMT) Val(158)Met polymorphism strongly influences prepulse inhibition (PPI) of the acoustic startle response (ASR) in healthy human volunteers. Given that schizophrenia patients exhibit impairment in PPI and that COMT is a putative susce...

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Detalhes bibliográficos
Main Authors: Quednow, Boris B., Wagner, Michael, Mössner, Rainald, Maier, Wolfgang, Kühn, Kai-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833112/
https://ncbi.nlm.nih.gov/pubmed/18635674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbn088
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