Inhibition of Ser/Thr Phosphatases Induces Capacitation-associated Signaling in the Presence of Src Kinase Inhibitors

Signaling events leading to mammalian sperm capacitation rely on activation/deactivation of proteins by phosphorylation. This cascade includes soluble adenylyl cyclase, an atypical bicarbonate-stimulated adenylyl cyclase, and is mediated by protein kinase A and the subsequent stimulation of protein...

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Autores principales: Krapf, Dario, Arcelay, Enid, Wertheimer, Eva V., Sanjay, Archana, Pilder, Stephen H., Salicioni, Ana M., Visconti, Pablo E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832948/
https://ncbi.nlm.nih.gov/pubmed/20068039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.085845
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