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IL-6 and MYC collaborate in plasma cell tumor formation in mice

Interleukin-6 (IL-6) plays a critical role in the natural history of human plasma cell neoplasms (PCNs), such as plasma cell myeloma and plasmacytoma (PCT). IL-6 is also at the center of neoplastic plasma cell transformation in BALB/c (C) mice carrying a transgene, H2-L(d)-IL6, that encodes human IL...

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Detalhes bibliográficos
Main Authors: Rutsch, Sebastian, Neppalli, Vishala T., Shin, Dong-Mi, DuBois, Wendy, Morse, Herbert C., Goldschmidt, Hartmut, Janz, Siegfried
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832814/
https://ncbi.nlm.nih.gov/pubmed/20018915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-237941
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