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Granzyme B is not required for regulatory T cell–mediated suppression of graft-versus-host disease

Regulatory T (T(reg)) cells can suppress a wide variety of immune responses, including antitumor and alloimmune responses. The mechanisms by which T(reg) cells mediate their suppressive effects depend on the context of their activation. We previously reported that granzyme B is important for T(reg)...

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Autors principals: Cai, Sheng F., Cao, Xuefang, Hassan, Anjum, Fehniger, Todd A., Ley, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832813/
https://ncbi.nlm.nih.gov/pubmed/19965675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233676
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