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Granzyme B is not required for regulatory T cell–mediated suppression of graft-versus-host disease

Regulatory T (T(reg)) cells can suppress a wide variety of immune responses, including antitumor and alloimmune responses. The mechanisms by which T(reg) cells mediate their suppressive effects depend on the context of their activation. We previously reported that granzyme B is important for T(reg)...

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Bibliographic Details
Main Authors: Cai, Sheng F., Cao, Xuefang, Hassan, Anjum, Fehniger, Todd A., Ley, Timothy J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832813/
https://ncbi.nlm.nih.gov/pubmed/19965675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233676
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