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Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement

Cytokines such as TNF and FASL can trigger death or survival depending on cell lines and cellular conditions. The mechanistic details of how a cell chooses among these cell fates are still unclear. The understanding of these processes is important since they are altered in many diseases, including c...

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Detalhes bibliográficos
Main Authors: Calzone, Laurence, Tournier, Laurent, Fourquet, Simon, Thieffry, Denis, Zhivotovsky, Boris, Barillot, Emmanuel, Zinovyev, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832675/
https://ncbi.nlm.nih.gov/pubmed/20221256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000702
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