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Amplitude histogram-based method of analysis of patch clamp recordings that involve extreme changes in channel activity levels

Many ion channels show low basal activity which is increased hundreds fold by the relevant gating factor. A classical example is the activation G protein activated K(+) channels (GIRK) by Gβγ subunit dimer. The extent of activation (relative to basal current), R(a), is an important physiological par...

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Detalhes bibliográficos
Main Authors: Yakubovich, Daniel, Rishal, Ida, Dessauer, Carmen W., Dascal, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832599/
https://ncbi.nlm.nih.gov/pubmed/18622586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-008-9117-z
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